Dissolution DNP Systems
Two dissolution DNP systems are available in our lab and are used mostly for methodological studies. One system is based on a wide-bore magnet charged to 3.4 T, corresponding to a 94 GHz ESR frequency. Recently, we have developed a new DNP system operating at 7.0 T static magnetic field (197 GHz ESR frequency).
An additional dissolution DNP system operating at 3.4 T is located in the laboratory of Prof. Kozerke at the Institute of Biomedical Engineering (IBT, ETH Zurich) and is used mostly for in-vivo applications.
Probes
For the different DNP systems available in our lab we have built several DNP probes.
One DNP probe, schematically described in figure, allows the sequential polarization and dissolution of up to six samples and can be used on all the 3.4 T systems. The probe is equipped with EPR and NMR detection capabilities to make mechanistic studies feasible under dissolution DNP conditions and to monitor the DNP build up.
A multi-sample probe allowing the independent dissolutions of up to 4 samples is also available for the 3.4 T systems. For methodological studies of the DNP processes that do not require subsequent dissolution, we have also built two simpler double-tuned DNP probes, available for both 3.4 and 7 T system.